Concentrated alkylamine/glucoprotamin based products are widely used chemical disinfectants for manual reprocessing of endoscopes in Central Europe. Products containing these active substances are highly effective against Mycobacteria including GA-resistant atypical species (Sekusept PLUS), other vegetative bacteria, fungi, and a wide range of viruses including Papilloma-virus. Using a contact time of 15 min they are effective in dilution rates between 1:25 to 1:33. For some applications lack of efficacy against some eneteroviruses and spores can be a disadvantage.
Alkylamine/glucoprotamin does not fix proteins and does not support biofilm creation. Available products based on these active substances are offered in combination with surfactants.They have an excellent cleaning performance and give the opportunity of removing small amounts of residue during the HLD in case of a prior non-proper cleaning procedure. Differences between glucoprotamin and alkylamine based products have been observed in terms of material compatibility and safety handling. In some cases skin irritation and an unpleasant smell are reported about alkylamine based products.